Affimer binders improve diagnostic assay performance for C.difficile detection


In a new study we have applied Affimer® technology to improve the specificity and sensitivity of a key diagnostic assay for the multi-antibiotic resistant Clostridium difficile.

The Affimer binders identified were:

  • Completely specific for the more virulent endotoxin form, toxin B, of C.difficile showing no cross-reactivity with toxin A found in current tests
  • Substituted into a commercial assay to confer specificity and sensitivity
  • Used to demonstrate how the application of Affimer reagents to current and developing diagnostic assays can offer increased specificity, sensitivity and stability.

Download the application note by completing the form.

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